BDBM10890 1-N-(3-chloro-1H-indol-7-yl)benzene-1,4-disulfonamide::CHEMBL77517::Compound 6::E7070::Indisulam (IND)::Sulfonamide, 7
SMILES NS(=O)(=O)c1ccc(cc1)S(=O)(=O)Nc1cccc2c(Cl)c[nH]c12
InChI Key InChIKey=SETFNECMODOHTO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 12 hits for monomerid = 10890
Affinity DataKi: 3nMAssay Description:Inhibition of human CA 12 catalytic domainMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition assay using carbonic anhydrases.More data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of human cloned transmembrane tumor-associated catalytic domain of carbonic anhydrase 12 preincubated for 15 mins by stopped flow CO2 hydr...More data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition constant against human carbonic anhydrase XIIMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of recombinant human transmembrane, tumor-associated form of carbonic anhydrase-12 preincubated for 15 mins by stopped flow CO2 hydration ...More data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of human cloned CA12 catalytic domain by CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of human transmembrane carbonic anhydrase 12 by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of human cloned catalytic domain of CA12 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of human cloned carbonic anhydrase 12 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of human membrane bound carbonic anhydrase 12 preincubated for 15 mins at room temperature followed by 72 hrs at 4 degC by stopped flow CO...More data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of human CA12 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Affinity DataKi: 3.40nMAssay Description:Inhibition of human cloned carbonic anhydrase 12 catalytic domain preincubated for 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair